ABSTRACT
·AIM:To observe the therapeutic effect of the mild form disseminated photocoagulation treatment for moderate non-proliferative diabetic retinopathy (MNPDR). ·METHODS: Prospective randomized controlled study. Totally 126 cases (209 eyes) with MNPDR were randomly assigned to two groups in ophthalmology department of Shanghai Shidong Hospital. There were 62 cases ( 103 eyes ) were treated with the mild form disseminated photocoagulation as the therapy group, 64 cases ( 106 eyes) were treated with control of blood glucose as the control group. All cases were followed up for 24mo. The best corrected visual acuity ( BCVA), fundus change and central visual field were observed and compared. · RESULTS: At 24mo after treatment, BCVA variety between two groups took on significant statistical difference which indicated that there were more eyes with improved or stable visual acuity in therapy group ( Hc=5. 942, P<0. 05). There was significant difference in fundus examination between two groups which indicated that there were more eyes with improved or stable fundus change in therapy group (Hc=12. 662, P<0. 05). There was no significant difference in average mean sensitivity (MS) between before and after laser therapy for 12mo (t=3. 1586, P>0. 05). During our follow-up, there were no complications likewise infection, hemorrhage, retinal membrane, injury of the macular fovear occurred. · CONCLUSION: The mild form disseminated photocoagulation therapy for moderate non-proliferative diabetic retinopathy is safe and effective without obvious complications, which can effectively delay the progression of diabetic retinopathy.
ABSTRACT
AIM: To evaluate the safety of the laser peripheral iridoplasty ( LPIP ) for the early-stage chronic primary angle-closure glaucoma ( ECPACG) . METHODS:Sixty-five eyes of 36 patients with ECPACG received LPIP. At preoperative and postoperative, patients were examined with intraocular pressure ( IOP ) , anterior chamber, optical coherence tomography ( OCT) , visual acuity, visual field, fundus and complications. The mean follow-up was 18. 2±6. 7mo (ranged 12~24mo). RESULTS: The preoperative average IOP were 23. 8±5.6mmHg, postoperative 1wk, 1, 3, 6, 12mo and in the last follow-up time the average IOP were 18. 7±3. 8, 17. 9±3. 2, 17. 6±3. 5, 18. 4±3. 7, 18. 6±3. 7, and 18. 6±7. 8mmHg. There was statistical difference comparing with preoperative (P0. 05). The postoperative visual acuity, visual field, fundus had not changed. There were no complications found. CONCLUSION:LPIP is safe, and has the short time effect in the treatment of ECPACG. With elapse of time, the effect of LPIP is weakened. We can repeat the treatment.